We present the measurement of the $\mathrm{B}^{+}$ meson production cross section as a function of transverse momentum and, for the first time, in charged particle multiplicity ranges using the CMS detector during $2016$ data collection that corresponds to an integrated luminosity of $175~\mathrm{nb^{-1}}$ , in proton-lead collisions at a per nucleon center of mass energy of $8.16~\mathrm{TeV}$. The results are in agreement with the fixed-order next-to-leading logarithmic calculations. Nuclear medium effects on $\mathrm{B}^{+}$ meson production are studied using the binary-collision scaled cross section ratio between events of different multiplicities from proton-lead collisions. The scaling factors in the ratio are determined using a novel approach based on the $Z\longrightarrow \mu^{-}\mu^{+}$ cross sections measured in the same events. The scaled ratio for $\mathrm{B}^{+}$ is consistent with unity for all event multiplicities, putting stringent constraints on nuclear modification for heavy flavor.

We present the measurement of the $\mathrm{B}^{+}$ meson production cross section as a function of transverse momentum and, for the first time, in charged particle multiplicity ranges using the CMS detector during $2016$ data collection that corresponds to an integrated luminosity of $175~\mathrm{nb^{-1}}$ , in proton-lead collisions at a per nucleon center of mass energy of $8.16~\mathrm{TeV}$. The results are in agreement with the fixed-order next-to-leading logarithmic calculations. Nuclear medium effects on $\mathrm{B}^{+}$ meson production are studied using the binary-collision scaled cross section ratio between events of different multiplicities from proton-lead collisions. The scaling factors in the ratio are determined using a novel approach based on the $Z\longrightarrow \mu^{-}\mu^{+}$ cross sections measured in the same events. The scaled ratio for $\mathrm{B}^{+}$ is consistent with unity for all event multiplicities, putting stringent constraints on nuclear modification for heavy flavor.