CONNIE is an experiment aimed at detecting reactor antineutrinos via the Standard Model CEvNS (coherent elastic neutrino-nucleus scattering) channel using pure silicon CCDs ionization detectors. Since 2021, the detector has been running with two Skipper-CCDs, lowering the detection threshold to 15 eVee, marking CONNIE as the first experiment to employ Skipper-CCDs for reactor neutrino detection. We report new results from 300 days of data from 2021-2022, with a reactor ON-OFF exposure of 14.9 and 3.5 g-days, respectively. From these data, we have derived a 95% C.L. limit on the CEvNS rate with Skipper-CCDs, which is comparable with the previous results from CONNIE using standard CCDs and longer exposure times. Based on these new findings, we conducted searches for Physics Beyond the Standard Model, focusing on exploring limits using a simplified model for light vector mediator, limits on scattering of dark matter on electrons by diurnal modulation, and a search for relativistic millicharged particles produced by reactors. We will discuss our current results and ongoing efforts to increase the detector mass.