The ICARUS collaboration operated the 760-ton T600 detector in a successful three-year physics run at the underground LNGS laboratory, conducting a sensitive search for LSND-like anomalous appearance in the CNGS beam. After a significant overhaul at CERN, the T600 detector was installed at Fermilab, where data collection for neutrino oscillation physics began in June 2022 using events from the Booster Neutrino Beam (BNB) and the off-axis Neutrinos at the Main Injector (NuMI) beam. ICARUS successfully completed its commissioning phase in June 2022, moving then to data taking for neutrino oscillation physics, aiming at first to either confirm or refute the claim by Neutrino-4 short-baseline reactor experiment. ICARUS will also measure neutrino cross sections in liquid argon with the NuMI beam and conduct several BSM searches. Soon, it will jointly search for evidence of sterile neutrinos with the Short-Baseline Near Detector (SBND). In this presentation, preliminary results from the ICARUS data with the BNB and NuMI beams are shown both in terms of performance of all ICARUS subsystems and of capability to select and reconstruct neutrino events.